Known as “America’s Distribution Center,” Memphis serves all regions of the country from its central location. It is the largest city in Tennessee, the third largest in the Southeast, and the 20th largest in the country. FedEx, a Fortune 500 company founded in Memphis, has its global headquarters and main hub here, contributing to the city having the world’s second-busiest cargo airport. Additionally, two other Fortune 500 companies (AutoZone and International Paper) have headquarters in Memphis. Healthcare, biomedical research, education, transportation, distribution and logistics are Memphis’ largest industries bringing more than $5 billion a year to the local economy. Memphis consistently ranks among the nation’s best commercial real estate markets, with office, warehouse and industrial lease rates among the nation’s lowest.